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Knee Pain: Causes, Symptoms, Diagnosis & Treatment | Spica Hospitals

Dr Deepak Garg
Dr Deepak Garg
Chief Sarcoma Surgeon
July 24, 2026
8 min read
Knee Pain: Causes, Symptoms, Diagnosis & Treatment | Spica Hospitals

Knee Pain: Causes, Symptoms, Diagnosis & Treatment

Knee pain is one of the most common reasons people visit an orthopaedic clinic. It can affect people of all ages—from young athletes with sports injuries to elderly individuals with arthritis.

While some knee pain improves with rest, persistent pain should never be ignored because early treatment often prevents permanent joint damage.


Human Knee MRI
Human Knee MRI

Illustration showing the major structures of the knee joint.


Why Does the Knee Hurt?

The knee is the largest joint in the human body and bears almost the entire body weight while walking, climbing stairs, running, or standing.

Pain may arise from:

  • Bones
  • Cartilage
  • Ligaments
  • Meniscus
  • Tendons
  • Muscles
  • Synovial lining
  • Infection
  • Tumors (rare)

Common Causes of Knee Pain

Cause Common Age Group Typical Symptoms
Osteoarthritis >50 years Pain while walking, stiffness
Ligament Injury Young adults Swelling after twisting injury
Meniscus Tear Young & Middle age Locking or clicking knee
Patellofemoral Pain Teenagers & Young adults Pain while climbing stairs
Rheumatoid Arthritis Any age Multiple joint pain
Gout Adults Sudden severe pain with swelling
Infection Any age Fever, severe pain, swelling
Bone Tumor (Rare) Any age Persistent pain, night pain

Clinical Pearl

Knee pain that wakes you up at night, is associated with unexplained swelling, or persists despite rest should always be evaluated by an orthopaedic specialist.


Symptoms You Should Never Ignore

Seek medical attention if you experience:

  • Persistent pain lasting more than two weeks
  • Inability to bear weight
  • Significant swelling
  • Knee deformity
  • Fever with knee pain
  • Locking of the knee
  • Recurrent instability
  • Night pain
  • Pain after a major injury

How Doctors Diagnose Knee Pain

Your orthopaedic surgeon may recommend:

Clinical Examination

  • Walking assessment
  • Joint movement
  • Ligament testing
  • Meniscus examination
  • Alignment assessment

Imaging Tests

Investigation Purpose
X-ray Arthritis, fractures
MRI Ligaments, cartilage, meniscus
CT Scan Complex fractures
Ultrasound Tendons & fluid collection
Bone Scan Selected conditions

MRI scan of the knee
MRI scan of the knee

MRI helps evaluate ligaments, cartilage, menisci, and other soft tissue structures.


Treatment Options

Treatment depends entirely on the underlying cause.

Conservative Treatment

Many patients improve without surgery.

This may include:

  • Activity modification
  • Weight reduction
  • Physiotherapy
  • Ice application
  • Knee braces
  • Pain-relieving medications
  • Lifestyle changes

Injection Therapy

Selected patients may benefit from:

  • Corticosteroid injections
  • Hyaluronic acid injections
  • Platelet-Rich Plasma (PRP) in carefully selected cases

Your orthopaedic surgeon will decide whether these treatments are appropriate for your condition.


Surgical Treatment

Surgery may be recommended when conservative treatment fails or in cases of significant structural damage.

Common procedures include:

  • Arthroscopy
  • Ligament reconstruction (ACL/PCL)
  • Meniscus repair
  • Cartilage restoration procedures
  • Osteotomy
  • Partial knee replacement
  • Total knee replacement

Can Knee Pain Be Prevented?

Yes. Many cases can be prevented by following healthy habits.

✅ Maintain a healthy body weight

✅ Exercise regularly

✅ Strengthen thigh muscles

✅ Warm up before sports

✅ Wear proper footwear

✅ Avoid sudden increase in activity


Frequently Asked Questions

Is every knee pain due to arthritis?

No. Knee pain can result from ligament injuries, meniscus tears, tendon problems, infections, inflammatory diseases, or, rarely, bone tumors.


When is MRI necessary?

MRI is usually recommended when soft tissue injuries such as ligament or meniscus damage are suspected or when X-rays do not explain persistent symptoms.


Can physiotherapy cure knee pain?

Physiotherapy is highly effective for many conditions, particularly muscle weakness, early arthritis, and certain sports injuries. The outcome depends on the underlying diagnosis.


Do all patients with arthritis need knee replacement?

No. Most patients are initially treated with medications, exercise, weight management, and physiotherapy. Knee replacement is generally considered when pain and disability remain severe despite appropriate non-surgical treatment.


When Should You Visit Spica Hospitals?

Consult an orthopaedic surgeon if you have:

  • Persistent knee pain
  • Difficulty walking
  • Swelling after injury
  • Recurrent instability
  • Knee locking
  • Night pain
  • Suspected ligament injury

Early diagnosis often leads to simpler and more effective treatment.


Conclusion

Knee pain should never be ignored, especially when it interferes with daily life or continues despite rest. Modern orthopaedic care offers a wide range of treatments—from physiotherapy and medications to minimally invasive surgery and joint replacement—allowing most patients to return to an active lifestyle.


Related Articles

  • When Does Knee Replacement Become Necessary?
  • Arthritis vs. Ligament Injury – How to Tell the Difference
  • Best Exercises for Healthy Knees
  • Weight Loss and Knee Pain: How They Are Connected

Need expert advice?

Book an appointment with the Orthopaedics team at Spica Hospitals for a comprehensive evaluation and personalized treatment plan.