Spica Healthcare β€” Unit of Grover Hospital, Bathinda
Advanced Surgical Protocol

Targeted Therapy for Colon Cancer

Evidence-based clinical protocol featuring sub-millimeter surgical precision, modular bio-compatible implants, Class-100 HEPA laminar flow suites, and fast-track rehabilitation at Grover Hospital, Bathinda.

15,000+Complex Surgeries
95%+Limb Salvage Benchmark
<0.3%Infection Rate Benchmark
100%Director-Led OPD & Surgeries
Biomarker-Driven BiologicsDirector's Signature Surgical Protocol

Precision Targeted Therapy & Biologics for Colon Cancer

Extended RAS/BRAF Biomarker Profiling & Targeted Monoclonal Antibodies

Dr. Neha Gupta delivers comprehensive precision targeted therapy and immunotherapy for metastatic colorectal cancer (mCRC). Utilizing upfront molecular testing for extended RAS (KRAS/NRAS exons 2, 3, 4), BRAF V600E, HER2 amplification, and Microsatellite Instability (MSI-H/dMMR), targeted monoclonal antibodies (anti-EGFR: Cetuximab/Panitumumab for RAS wild-type left-sided colon tumors, anti-VEGF: Bevacizumab, and Encorafenib for BRAF mutations) are combined with doublet/triplet chemotherapy (FOLFOX, FOLFIRI, FOLFOXIRI) to shrink liver/lung metastases and convert inoperable disease into surgically resectable cures.

Extended RAS & BRAF Testing: Guides exact choice between anti-EGFR (Cetuximab) and anti-VEGF (Bevacizumab)
Conversion to Resectability: Shrinks metastatic liver lesions to enable curative liver surgery in 30%+ of patients
MSI-High Immunotherapy (Pembrolizumab): Replaces toxic chemotherapy with powerful immunotherapy for dMMR tumors
Targeted BRAF V600E Regimens: Encorafenib + Cetuximab overcoming historically aggressive mutations

Lead Operating Specialists (1)

Specialist directors and senior surgeons performing this procedure.

Dr. Neha Gupta - Clinical Director & Senior Medical Oncologist

Dr. Neha Gupta

Senior Consultant & Clinical Director β€” Medical Oncology

13+ Years Clinical Exp

Grover Hospital BathindaView Profile

Clinical Indications (Who Requires This Procedure?)

Primary clinical criteria and symptoms that indicate the need for this procedure.

Newly diagnosed metastatic colorectal cancer requiring first-line targeted therapy + chemotherapy.
RAS (KRAS/NRAS) wild-type left-sided colon cancer eligible for anti-EGFR targeted antibody therapy.
BRAF V600E mutation-positive metastatic colorectal cancer requiring targeted doublet/triplet therapy.
Microsatellite Instability-High (MSI-H / dMMR) metastatic colon cancer requiring first-line Pembrolizumab.

Step-by-Step Surgical Patient Journey

What happens before, during, and immediately after the procedure at Grover Hospital.

1

Molecular Profiling & Sidedness Staging

NGS / PCR testing of biopsy tissue for KRAS, NRAS, BRAF V600E, HER2, and MSI/MMR status.

2

Targeted Regimen Selection

Selection of optimal targeted partner (Cetuximab vs Bevacizumab) based on primary tumor sidedness and RAS status.

3

Daycare Targeted Delivery

Outpatient 2-weekly targeted infusion in Daycare suite with prophylactic skin care protocols.

4

Periodic Imaging & CEA Tracking

Tri-monthly contrast CT scans and CEA marker tracking to evaluate tumor shrinkage and surgical conversion.

Recovery & Rehabilitation Milestones

Expected healing trajectory, weight-bearing timeline, and return-to-activity guide.

Phase 1: Genomic Staging & First Infusion

Molecular RAS/BRAF/MSI panel review, baseline staging CT chest/abdomen/pelvis, daycare targeted infusion.

Cycle 1 (Day 1)

Phase 2: Active Targeted Treatment Phase

2-weekly targeted chemo-biologic cycles, skin acneiform rash management (anti-EGFR), CEA tracking.

Month 1 – 3

Phase 3: Resectability & Response Assessment

Restaging CT scan and multidisciplinary liver surgery board review for potential curative metastasectomy.

Month 3 – 4

Phase 4: Maintenance & Long-Term Control

Ongoing targeted maintenance therapy achieving sustained disease control and long-term survival.

Month 6 – Long Term

Clinical Infrastructure & Technology Suite

High-definition glimpse into our surgical suites, robotic systems, and patient facilities at Grover Hospital, Bathinda.

ISO Class-100 Laminar Airflow Operation Theatres
Zero-Infection OT

ISO Class-100 Laminar Airflow Operation Theatres

Positive-pressure ultra-clean surgical suites with 99.97% HEPA filtration for joint & tumor surgery.

3D Computer-Navigated Robotic Surgical Suite
3D Robotics & Navigation

3D Computer-Navigated Robotic Surgical Suite

Intraoperative optical tracking ensuring 0.1mm alignment accuracy and negative oncological margins.

In-Hospital Physical Rehabilitation & Gait Clinic
Fast-Track Rehab

In-Hospital Physical Rehabilitation & Gait Clinic

Dedicated post-op recovery gym equipped for Day-1 walking, CPM passive motion, and balance conditioning.

Spica Healthcare & Grover Hospital Main Campus
Main Facility

Spica Healthcare & Grover Hospital Main Campus

Modern multi-speciality tertiary surgical institute with 24/7 emergency trauma ICU on GT Road, Bathinda.

Verified Patient Outcomes

Real recoveries treated by our surgical directors.

β˜… 4.9 / 5.0

"Targeted PARP Inhibitors and Complete Remission with Dr. Neha Gupta"

β˜…β˜…β˜…β˜…β˜…

"After completing ovarian cancer chemotherapy, genetic testing by Dr. Neha Gupta revealed a BRCA gene mutation. She placed me on oral Olaparib maintenance tablets at home. My CA-125 is completely normal at 8 U/mL and my scans show zero evidence of disease after 2 years!"

β€” Paramjit Kaur (Faridkot)Case Study β†’

"Instant Sciatica Nerve Relief Through 16mm Keyhole Micro-Endoscopic Surgery"

β˜…β˜…β˜…β˜…β˜…

"An L5-S1 disc herniation caused shooting electric pain down my left leg, leaving me unable to stand straight for 2 months. Dr. Deepak Garg performed Micro-Endoscopic Discectomy through a 16mm keyhole port without any spinal fusion or screws. The shooting pain disappeared immediately upon waking up, and I was discharged the next morning!"

β€” Rajesh Kumar (Bathinda)Case Study β†’

Why Choose Spica Healthcare for Targeted Therapy for Colon Cancer?

Tertiary hospital surgical expertise combined with 100% cashless insurance support at Grover Hospital, Bathinda.

Next-Gen Sequencing (NGS)

Comprehensive multi-gene panel testing detecting actionable oncogenic driver mutations.

Personalized Drug Matching

Selecting targeted small-molecule inhibitors matched to individual genetic aberrations.

Hereditary Cancer Genetics

Identifying familial cancer predispositions (BRCA1/2, Lynch Syndrome) for proactive family care.

Liquid Biopsy Monitoring

Periodic cell-free DNA blood testing tracking treatment response and early minimal residual disease.

Frequently Asked Questions

RAS (KRAS and NRAS) and BRAF are genes inside colon cancer cells. If the RAS genes are normal ('wild-type'), targeted drugs called anti-EGFR inhibitors (like Cetuximab) work exceptionally well to shrink tumors. If RAS is mutated, anti-VEGF drugs (like Bevacizumab) are used instead. Molecular testing ensures you get the right drug.

First Visit Checklist: Essential Documents to Bring

Please bring the following records so our surgical team can evaluate Targeted Therapy for Colon Cancer candidacy in one visit:

βœ“
Original Biopsy, Histopathology, and NGS Genomic Profiling reports
βœ“
Latest Whole-Body PET-CT scan films and DICOM CD discs
βœ“
Recent Complete Blood Count (CBC), LFT, and Kidney Function (KFT) blood reports

Book Consultation

Dr. Neha Gupta

Consultation Feeβ‚Ή500
100% Cashless & Ayushman Empanelled

All surgeries, modular titanium implants, and hospital admissions covered under PM-JAY and major private insurance TPAs.

Director-Led Clinical Breakthroughs

Signature Surgical Innovations & Techniques

Proprietary surgical methodologies and precision protocols pioneered by our senior directors to minimize trauma, protect natural anatomy, and accelerate recovery.

1 of 13
Comprehensive Bone Cancer Oncology & Limb Preservation
Click to Watch Video Demonstration
95%+ Limb Salvage & MAP Chemotherapy
Multidisciplinary Limb Salvage, MAP Chemotherapy & Modular Megaprosthetics

Comprehensive Bone Cancer Oncology & Limb Preservation

Dr. Deepak Garg (Orthopaedic Surgical Oncology - RGCI Delhi Trained) and Dr. Neha Gupta (Medical Oncology) co-lead the Bone Cancer & Sarcoma Center at Spica Healthcare. Integrating intensive multi-agent neoadjuvant chemotherapy protocols (MAP: High-Dose Methotrexate, Doxorubicin, Cisplatin for Osteosarcoma; VIDE: Vincristine, Ifosfamide, Doxorubicin, Etoposide for Ewing Sarcoma) with 3D computer-navigated limb salvage surgery and modular titanium megaprosthetic joint reconstruction, 5-year survival rates exceed 75% to 80% while saving over 95% of patients from limb amputation.

Key Advantages Over Conventional Surgery:
Coordinated Surgical & Medical Oncology: Seamless dual leadership under Dr. Deepak Garg & Dr. Neha Gupta
95%+ Limb Preservation Rate: Wide oncological bone resection avoiding traumatic limb amputations
High-Grade Sarcoma Chemotherapy: Standardized MAP and VIDE protocols delivering high tumor necrosis rates (>90%)
Custom Modular Megaprostheses: Immediate joint restoration with biological tendon ingrowth collars
Why Families & Physicians Trust Spica

World-Class Clinical Precision, Built on Compassion

Spica Healthcare β€” Bone and Cancer Institute, Bathinda β€” is South-Western Punjab's premier super-speciality centre led by AIIMS and Tata Memorial fellowship-trained directors.

AIIMS & Tata Memorial Alumni25+ Yrs Combined Senior Leadership

15,000+ Complex Surgeries & 100% Director-Led Evaluations

Every diagnostic MRI review, surgical staging, and operation is personally directed by chief clinical specialists β€” Dr. Deepak Garg (Orthopaedic Oncology & Robotics) and Dr. Neha Gupta (Medical Oncology) β€” guaranteeing zero junior proxies.

15,000+Surgeries Completed
95%+Limb Salvage Rate
<0.3%Infection Benchmark
Pre-Op 3D Virtual Planning 100% Direct Director OPD Day-1 Walking Protocol
Sub-Millimeter Accuracy

3D Navigated Robotics & Day-1 Walking

Sub-millimeter implant positioning and soft-tissue ligament balancing ensuring patients walk comfortably within 24 hours of total knee replacement.

ROSA Robotics & Stryker Nav
Malwa Punjab Exclusive

Limb-Salvage Over Amputation

South-West Punjab's only dedicated centre for modular titanium megaprosthesis, saving natural limbs and functions in 95%+ of bone cancer patients.

Modular Megaprosthesis
0-Out-Of-Pocket Options

100% Cashless PM-JAY & TPAs

Full cashless coverage for Ayushman Bharat (PM-JAY), Punjab Govt Health Schemes, ECHS, and 30+ private insurance networks with on-desk approvals.

Ayushman + 30+ TPAs Empanelled
24/7 Tertiary Ready

Class-100 Laminar Flow OTs & ICU

Positive-pressure HEPA filtered theatres minimizing infection rates below international benchmarks with 24/7 dedicated critical care backup.

Spica Healthcare Bathinda
Expert Surgical Directors

Meet the Doctors at Spica Healthcare

Fellowship-trained surgical directors from AIIMS & Tata Memorial providing compassionate, world-class tertiary care in super-speciality orthopaedics and medical oncology.

Dr. Neha Gupta - Clinical Director & Senior Medical Oncologist

Dr. Neha Gupta

Senior Consultant & Clinical Director β€” Medical Oncology

13+ Yrs Exp

MBBS (BFUHS Faridkot), MD Radiation Oncology (BFUHS Faridkot), DrNB Medical Oncology (Sarvodaya Hospital, Faridabad), Precision Oncology (Harvard, USA), Ex Consultant RGCI New Delhi

Medical Oncology & ChemotherapyImmunotherapy & Targeted OncologyPrecision Oncology & Cancer GenomicsPreventive Cancer ScreeningPalliative & Supportive OncologyHormonal TherapyComprehensive Cancer Treatments
Dr. Deepak Garg - Director & Senior Joint Replacement, Spine and Orthopaedic Oncologist

Dr. Deepak Garg

Senior Consultant & Clinical Director β€” Orthopaedic Oncology & Robotic Joint Surgery

16+ Yrs Exp

MBBS (TNMC Mumbai), DNB Orthopaedics (PGI & SP Miraj), Fellowship Arthroplasty and Arthroscopy (Fortis Hospital, New Delhi), Fellowship Orthopaedic Oncology (Rajiv Gandhi Cancer Institute, New Delhi)

Orthopaedic Oncology & Bone Tumors3D Robotic Joint ReplacementSports Injuries & ArthroscopyTrauma & Fracture ReconstructionGeneral Orthopaedics & Spine CareComprehensive Cancer Treatments
Community Health & Academic Outreach

Upcoming Health Camps & Academic Events

Free OPD screening camps, director-led masterclasses, and national oncology representations by Spica Healthcare.

Curious what families & patients experience

Hear what our patients are saying

Real stories from patients who recovered through limb preservation surgery, 3D robotic joint replacements, and precision cancer care at Spica Healthcare β€” Grover Hospital, Bathinda.

Health Knowledge & Clinical Guides

Doctor-Authored Health Guides

Evidence-based surgical recovery roadmaps, robotic joint protocols, and precision oncology insights written by our clinical directors.